15/09/2022 By acomputer 527 Views

Atopic dermatitis

The skin is a natural barrier which protects us in particular from the substances with which our body comes into contact (clothes, perfumes, cosmetics, food, etc..) each day.It also ensures the exchange of humidity and warmth between our body and the environment.

In people with atopic dermatitis, this natural defense is affected due to a genetic predisposition - as the term "atopic" indicates - resulting in excessive skin reactivity with regard to the substances present in the environment and allergens.

In addition to this genetic vulnerability, inflammatory processes come into play.An imbalance (reduced production of antimicrobial peptides - natural antibiotics), deficiency or dysfunction in substances (lipids, proteins, enzymes, moisturizing molecules, etc..) which constitute the superficial layer of the skin weaken its protective function.The skin retains water less effectively and becomes dry, which makes it more vulnerable to viral, bacterial and mycotal infections, allergens and substances present in the environment.When they are in touch, the latter will then trigger an excessive inflammatory reaction.Redness, swelling, pain ... and it is a vicious circle that settles.

Dermatite atopique

Finally, environmental factors are also involved in the trigger or maintenance of the disease, among them:

The incidence of these factors varies from person to person and depending on the moments of life, so that it is difficult to identify what truly triggers a push.